Manchester City boss Pep Guardiola is being made to sweat over the fitness of Erling Haaland ahead of his side's fixture against Burnley on Saturday, with the towering Norwegian striker still struggling with a back injury ahead of the weekend.
Haaland, who has six goals in five Premier League outings already this season, limped off during Sunday's hard-fought 1-1 draw with Arsenal, yet Guardiola remains hopeful that his in-form forward will still feature.
Elsewhere, Liverpool's Hugo Ekitike misses out through suspension after receiving a ludicrous second yellow card for taking his shirt off while celebrating the winner in the Reds' 2-1 victory over Southampton in the EFL Cup on Tuesday.
Manchester United's Casemiro also misses out through suspension, while the injured Cole Palmer will be a big miss for Chelsea ahead of their match against Brighton on Saturday.
Take a look at every player who's missing or doubtful ahead of this weekend's Premier League fixtures:
Brentford v Manchester United
WON'T PLAY
Gustavo Nunes | Hamstring Injury
Maghoma P. | Hamstring Injury
Casemiro | Red Card
Martinez Li. | Knee Injury
Chelsea v Brighton
WON'T PLAY
Badiashile B. | Knock
Buonanotte F. | Loan agreement
Colwill L. | Knee Injury
Delap L. | Hamstring Injury
Essugo D. | Thigh Injury
Lavia R. | Muscle Injury
Mudryk M. | Suspended
Palmer C. | Groin Injury
Hinshelwood J. | Ankle Injury
March S. | Knee Injury
Webster A. | Knee Injury
DOUBTFUL
Acheampong J. | Illness
Guiu M. | Injury
De Cuyper M. | Injury
Crystal Palace v Liverpool
WON'T PLAY
Benitez W. | Finger Injury
Doucoure C. | Knee Injury
Kporha C. | Back Injury
Pino Y. | Knee Injury
Riad C. | Knee Injury
Bajcetic S. | Hamstring Injury
Chambers L. | Back Injury
Ekitike H. | Red Card
Leoni G. | Knee Injury
Scanlon C. | Hamstring Injury
Leeds v Bournemouth
WON'T PLAY
Lucas Perri | Thigh Injury
Smith A. | Hamstring Injury
Soler J. | International duty
Unal E. | Knee Injury
DOUBTFUL
Bogle J. | Foot Injury
Gnonto W. | Calf Injury
James D. | Injury
Cook L. | Shoulder Injury
Manchester City v Burnley
WON'T PLAY
Ait Nouri R. | Ankle Injury
Cherki R. | Thigh Injury
Khusanov A. | Ankle Injury
Kovacic M. | Achilles Tendon Injury
Marmoush O. | Knee Injury
Amdouni Z. | Knee Injury
Beyer J. | Hamstring Injury
Roberts C. | Groin Injury
DOUBTFUL
Haaland E. | Lower Back Injury
Bruun Larsen J. | Knock
Nottingham Forest v Sunderland
WON'T PLAY
Aina O. | Hamstring Injury
Dominguez N. | Knee Injury
Cirkin D. | Wrist Injury
Diarra H. | Groin Injury
Hjelde L. F. | Achilles Tendon Injury
Mandava R. | Red Card
Mundle R. | Hamstring Injury
O'Nien L. | Shoulder Injury
DOUBTFUL
Douglas Luiz | Hamstring Injury
Murillo | Injury
Alese A. | Shoulder Injury
Tottenham v Wolves
WON'T PLAY
Bissouma Y. | Knee Injury
Dragusin R. | Knee Injury
Kulusevski D. | Knee Injury
Maddison J. | Knee Injury
Andre | Injury
Chiwome L. | Knee Injury
DOUBTFUL
Davies B. | Knee Injury
Kolo Muani R. | Thigh Injury
Solanke D. | Ankle Injury
Takai K. | Foot Injury
Aston Villa v Fulham
WON'T PLAY
Onana A. | Hamstring Injury
Tielemans Y. | Calf Injury
None
DOUBTFUL
Barkley R. | Lacking Match Fitness
Newcastle v Arsenal
WON'T PLAY
TBC
TBC
DOUBTFUL
TBC
Everton v West Ham
WON'T PLAY
TBC
TBC
DOUBTFUL
TBC