Carlton v Richmond (Thursday, 7:30pm AEDT)
Carlton: Hudson O'Keefe, Matthew Carroll and Lachlan Cowan are in for Liam Reidy, Ashton Moir and Adam Saad.
FB: Lachlan Cowan, Jacob Weitering, Harry Dean
HB: Mitch McGovern, Lewis Young, Oliver Florent
C: Campbell Chesser, Patrick Cripps, Elijah Hollands
HF: Ben Ainsworth, Harry McKay, Will Hayward
FF: Jagga Smith, Brodie Kemp, Lachie Fogarty
R: Marc Pittonet, George Hewett, Sam Walsh
(IC: Zac Williams, Cooper Lord, Elijah Hollands, Matthew Carroll, Hudson O'Keefe)
Richmond: Sam Grlj makes his club debut. Maurice Rioli plays his 50th game.
FB: Noah Balta, Ben Miller, Nathan Broad
HB: Sam Banks, Sam Grlj, Jayden Short
C: Hugo Ralphsmith, Sam Lalor, Kane McAuliffe
HF: Seth Campbell, Maurice Rioli, Rhyan Mansell
FF: Jonty Faull, Tom Lynch, Harry Armstrong
R: Toby Nankervis, Tim Taranto, Jack Ross
(IC: James Trezise, Josh Gibcus, Jacob Hopper, Steely Green, Campbell Gray)
Essendon v Hawthorn (Friday, 7:40pm AEDT)
Essendon: Max Kondogiannis, Dyson Sharp, Hussien El Achkar and Brayden Fiorini make their club debuts.
FB: Jaxon Prior, Ben McKay, Zach Reid
HB: Archie Roberts, Mason Redman, Andrew McGrath
C: Xavier Duursma, Jye Caldwell, Brayden Fiorini
HF: Sam Durham, Nate Caddy, Archie Perkins
FF: Hussien El Achkar, Peter Wright, Kyle Langford
R: Lachlan Blakiston, Darcy Parish, Zach Merrett
(IC: Dyson Sharp, Archer May, Max Kondogiannis, Zak Johnson, Jayden Nguyen)
Hawthorn: Cameron McKenzie and Ned Reeves are in for Harry Morrison and Finn Maginness.
FB, Karl Amon, Thomas Barrass, Jarman Impey
HB: Josh Battle, James Sicily, Blake Hardwick
C: Dylan Moore, Cameron Mackenzie, Massimo D'Ambrosio
HF: Sam Butler, Mitchell Lewis, Nick Watson
FF: Connor MacDonald, Mabior Chol, Jack Gunston
R: Lloyd Meek, Jai Newcombe, Conor Nash
(IC: Jack Scrimshaw, Jack Ginnivan, Josh Ward, Josh Weddle, Ned Reeves)
Western Bulldogs v GWS Giants (Saturday, 1:15pm AEDT)
Western Bulldogs: Will Lewis and Ryley Sanders are in for Artie Jones and Jordan Croft.
FB: Lachie Jaques, Buku Khamis, Rory Lobb
HB: Connor Budarick, James O'Donnell, Bailey Dale
C: Sam Davidson, Marcus Bontempelli, Bailey Williams
HF: Rhylee West, Sam Darcy, Joel Freijah
FF: Will Lewis, Aaron Naughton, Tom Liberatore
R: Tim English, Matthew Kennedy, Ed Richards
(IC: Michael Sellwood, Oskar Baker, Cooper Hynes, Ryley Sanders, Lachie Bramble)
GWS Giants: There are no debuts or milestones.
FB: Jayden Laverde, Jack Buckley, Connor Idun
HB: Lachie Ash, Lachie Whitfield, Joe Fonti
C: Harvey Thomas, Clayton Oliver, Ryan Angwin
HF: Phoenix Gothard, Jake Riccardi, Stephen Coniglio
FF: Jake Stringer, Jesse Hogan, Max Gruzewski
R: Kieren Briggs, Toby Greene, Finn Callaghan
(IC: Harry Himmelberg, Harry Rowston, Josaia Delana, Xavier O'Halloran, Callum M Brown)
Geelong v Fremantle (Saturday, 4:15pm AEDT)
Geelong: Jeremy Cameron, Patrick Dangerfield and club debutant Mitch Edwards are in for Oliver Henry, James Worpel and Mitch Knevitt.
FB: Connor O'Sullivan, Jack Henry, Sam De Koning
HB: Tom Stewart, Oisin Mullin, Lawson Humphries
C: Mark O'Connor, Bailey Smith, Oliver Dempsey
HF: Bradley Close, Shaun Mannagh, Jack Martin
FF: Jeremy Cameron, Shannon Neale, Patrick Dangerfield
R: Mark Blicavs, Tom Atkins, Max Holmes
(IC: Zach Guthrie, Jhye Clark, Tanner Bruhn, Gryan Miers, Mitchell Edwards)
Fremantle: Judd McVee makes his club debut.
FB: Karl Worner, Oscar McDonald, Heath Chapman
HB: Jordan Clark, Alex Pearce, Judd McVee
C: Corey Wagner, Andrew Brayshaw, Matthew Johnson
HF: Isaiah Dudley, Patrick Voss, Sam Switkowski
FF: Shai Bolton, Josh Treacy, Murphy Reid
R: Sean Darcy, Luke Jackson, Caleb Serong
(IC: Brandon Walker, Jye Amiss, Nathan O'Driscoll, Neil Erasmus, Hayden Young)
Sydney v Brisbane (Saturday, 7:10pm AEDT)
Sydney: Matt Roberts plays his 50th game.
FB: Callum Mills, Tom McCartin, Dane Rampe
HB: Lewis Melican, Nick Blakey, Jai Serong
C: Riley Bice, Justin McInerney, Matthew Roberts
HF: Malcolm Rosas, James Rowbottom, Tom Papley
FF: Joel Amartey, Charlie Curnow, Isaac Heeney
R: Brodie Grundy, Errol Gulden, Chad Warner
(IC: Sam Wicks, Angus Sheldrick, James Jordon, Jake Lloyd, Logan McDonald)
Brisbane: Sam Draper, Lincoln McCarthy, Daniel Annable, James Tunstill and Noah Answerth are in for Darcy Gardiner, Harris Andrews, Zac Bailey, Hugh McCluggage and Logan Morris.
FB: Keidean Coleman, Zane Zakostelsky, Ryan Lester
HB: Darcy Wilmot, Jaspa Fletcher, Dayne Zorko
C: Bruce Reville, Will Ashcroft, Jarrod Berry
HF: Charlie Cameron, Oscar Allen, Levi Ashcroft
FF: Sam Draper, Cameron Rayner, Ty Gallop
R: Darcy Fort, Josh Dunkley, Lachie Neale
(IC: Kai Lohmann, Lincoln McCarthy, Dan Annable, James Tunstill, Noah Answerth)
Collingwood v Adelaide (Saturday, 7:35pm AEDT)
Collingwood: Dan McStay plays his 200th game.
FB: Billy Frampton, Isaac Quaynor, Brayden Maynard
HB: Dan Houston, Josh Daicos, Jack Crisp
C: Edward Allan, Nick Daicos, Patrick Lipinski
HF: Lachlan Schultz, Jordan De Goey, Beau McCreery
FF: Tim Membrey, Jamie Elliott, Daniel McStay
R: Darcy Cameron, Scott Pendlebury, Harry Perryman
(IC: Wil Parker, Steele Sidebottom, Ned Long, Jack Buller, Roan Steele)
Adelaide: Callum Ah Chee, Lachlan McAndrew and Toby Murray make their club debuts.
FB: Wayne Milera, Jordon Butts, Hugh Bond
HB: Nick Murray, Josh Worrell, Rory Laird
C: Brayden Cook, Jordan Dawson, Isaac Cumming
HF: Luke Pedlar, Riley Thilthorpe, Callum Ah Chee
FF: Josh Rachele, Taylor Walker, Darcy Fogarty
R: Lachlan McAndrew, Sam Berry, Jake Soligo
(IC: Toby Murray, James Peatling, Alex Neal-Bullen, Max Michalanney, Ben Keays)
North Melbourne v Port Adelaide (Sunday, 1:10pm AEDT)
North Melbourne: Lachy Dovaston and Tom Blamires make their club debuts.
FB: Toby Pink, Griffin Logue, Charlie Comben
HB: Finn O'Sullivan, Caleb Daniel, Tom Blamires
C: Jy Simpkin, Tom Powell, Dylan Stephens
HF: Paul Curtis, Cooper Trembath, Jacob Konstanty
FF: Cameron Zurhaar, Nick Larkey, Lachy Dovaston
R: Tristan Xerri, Luke Davies-Uniacke, Harry Sheezel
(IC: Zane Duursma, Colby McKercher, Luke McDonald, Callum Coleman-Jones, Luke Parker, Jack Darling, Zac Banch, Robert Hansen Jr)
Port Adelaide: Jacob Wehr, Corey Durdin and Jack Watkins make their club debuts.
FB: Lachlan Jones, Esava Ratugolea, Todd Marshall
HB: Miles Bergman, Aliir Aliir, Kane Farrell
C: Jase Burgoyne, Connor Rozee, Jacob Wehr
HF: Jason Horne-Francis, Mitch Georgiades, Joe Berry
FF: Darcy Byrne-Jones, Jack Whitlock, Joe Richards
R: Dante Visentini, Zak Butters, Willem Drew
(IC: Corey Durdin, Jackson Mead, Ollie Lord, Jack Lukosius, Jordon Sweet, Ewan Mackinlay, Logan Evans, Jack Watkins)
Melbourne v St Kilda (Sunday, 3:15pm AEDT)
FB: Harrison Petty, Jake Lever, Blake Howes
HB: Changkuoth Jiath, Daniel Turner, Christian Salem
C: Xavier Lindsay, Jack Steele, Ed Langdon
HF: Kysaiah Pickett, Jacob van Rooyen, Tom Sparrow
FF: Bayley Fritsch, Brody Mihocek, Kade Chandler
R: Max Gawn, Caleb Windsor, Harvey Langford
(IC: Koltyn Tholstrup, Jai Culley, Jake Melksham, Trent Rivers, Tom McDonald, Max Heath, Harry Sharp, Latrelle Pickett)
St Kilda: Rowan Marshall is out. Liam Stocker, Isaac Keeler, Alex Dodson and Charlie Banfield join the extended bench.
FB: Jack Silvagni, Callum Wilkie, Anthony Caminiti
HB: Alixzander Tauru, Bradley Hill, Nasiah Wanganeen-Milera
C: Marcus Windhager, Max Hall, Darcy Wilson
HF: Mattaes Phillipou, Hugh Boxshall, Mitchito Owens
FF: Liam Ryan, Cooper Sharman, Jack Higgins
R: Tom De Koning, Sam Flanders, Jack Sinclair
(IC: Jack Macrae, Liam Stocker, Isaac Keeler, Jack Carroll, Alex Dodson, Mason Wood, Hugo Garcia, Charlie Banfield)
Gold Coast v West Coast (Sunday, 6:10pm AEDT)
Gold Coast: Jed Walter, Ned Moyle, Caleb Graham join the extended bench.
FB: Mac Andrew, Bodhi Uwland, Sam Collins
HB: John Noble, Daniel Rioli, Joel Jeffrey
C: Lachie Weller, Wil Powell, Sam Clohesy
HF: Touk Miller, Bailey Humphrey, Will Graham
FF: Ethan Read, Ben King, Leo Lombard
R: Jarrod Witts, Noah Anderson, Christian Petracca
(IC: Jed Walter, Alex Davies, Ned Moyle, Ben Long, Zeke Uwland, Caleb Graham, Oscar Adams, Jy Farrar)
FB: Reuben Ginbey, Tylar Young, Bo Allan
HB: Liam Duggan, Brady Hough, Josh Lindsay
C: Hamish Davis, Elliot Yeo, Deven Robertson
HF: Jack Graham, Jobe Shanahan, Willem Duursma
FF: Archer Reid, Jake Waterman, Jamie Cripps
R: Matthew Flynn, Harley Reid, Tom McCarthy
(IC: Tim Kelly, Cooper Duff-Tytler, Ryan Maric, Thomas Cole, Rhett Bazzo, Finlay Macrae, Jacob Newton, Milan Murdock)