Curry, 38, revealed the deal on social media and called it "the partnership of a lifetime" that will include global expansion of his Curry Brand, basketball products, a golf line, leisure clothing, and the ability to sign other athletes to his brand.
"This is bigger than a show deal, bigger than a signature series," Curry said in a video, saying Li-Ning will deliver "sneakers that I believe in that will continue to deliver at the highest level."
Other Li-Ning athletes with their shoes include Dwyane Wade and Jimmy Butler, Curry's Golden State Warriors teammate.
Curry had been a partner with Under Armour for 13 years before the split and had worn various brands through the NBA season.