The Gunners have Sesko on their shortlist as they seek a new centre-forward signing this summer.
The Telegraph says Arsenal have made enquiries with Leipzig and been informed that Sesko won't leave for less than €110 million (£92.5m).
Leipzig's management are confident of their bargaining position given that Sesko signed a new deal just a year ago to 2029.
Arsenal see Sesko as an alternative to Sporting Lisbon goal-machine Viktor Gyokeres, whose agents met with Arsenal officials last weekend.